血府逐瘀湯對硬皮症患者微循環療效之評估

張恒鴻
台北市立中
硬皮症合併微循環障礙之患者，目前尚無有效的療法。由於其臨床表現與病理特徵，與中醫“寒凝血瘀症”相當。本研究擬以“血府逐瘀湯”合併西藥治療，追蹤患者微循環的改善。並從微循環之變化偵測其對內臟功能之影響。

由風濕科門診篩檢合於硬皮症合併微循環障礙之條件的患者20名，進行本項研究。所有的患者均接受心、肺、胃腸道及腎臟功能之評估，以知其內臟受侵犯的程度。依患者之意願分為二組，一組為實驗組，給予“血府逐瘀湯”；另一組為對照組，依現代醫學公認之治療標準給予硬皮症之傳統治療藥物。兩組均連續治療6個月，治療前及治療後每三個月接受一次微循環之檢查，及每半年接受一次內臟功能之評估。

關鍵字：硬皮症 微循環 寒凝血瘀 血府逐瘀湯

The effect of SFU on the microcirculatory disturbance of progressive systemic sclerosis

Hen-Hong Chang
Taipei City Hospital Of Traditional Chinese Medicine
Progressive systemic sclerosis (PSS, Scleroderma) is a multisystemic disorder of unknown cause, characterized by fibrosis of skin, blood vessels and visceral organs including gastrointestinal tract, lungs, heart and kidney. Most of the patients have impairement of microcirculation and there is no satisfactory treatment. The clinical manifestations of scleroderma are compatible with “血瘀”in traditional Chinese medicine. The study use herb prescription “SFT” in addition to the conventional treatment for scleroderma.

We collect 20 patients of scleroderma with impaired microcirculation in this study. All patients evaluate the function of heart, lungs, G-I tract and kidneys. SFT is given in experimental group, but only conventional treatment in control group. All patients receive six-month treatment, and repeat examination for microcirculation every three months. All patients receive examinations for evaluation of internal organs at the six-month interval.

關鍵字：Systemic sclerosis Microcirculation Traditional Chinese Medicin