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四種常用中藥材輻射滅菌後對其療效指標成分的影響研究 陳家杰原子能委員 |
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| 省地區屬潮濕高溫的氣候，中藥材的保存不易，常有長霉生蟲的問題發生。以鈷六十γ射線照射來滅菌的方法，因快速及滅菌效果佳，受到中藥業者採用。以γ射線照射滅菌後，大多只注意滅菌殺蟲效果，對γ射線之不同照射劑量，是否會破壞中藥材有效成分，或影響中藥材貯存之安定性，則較少探討。本實驗以白芍藥、甘草、西洋、冬蟲夏草參為實驗樣本分別照射10, 15, 20, 30 KGy 之γ射線劑量後，就其具療效之指標成分(甘草：Glycyrrhizin；西洋參：Ginsenoside Rb1, Rg1；白芍藥：Paeoniflorin、冬蟲夏草：蟲草素)以HPLC加以分析、比較照射前後其指標成分含量是否改變，來評估是否會影響中藥材之療效成分，並檢測四種照射劑量之滅菌效果。本研究計劃將分別對甘草、西洋參、白芍藥、冬蟲夏草探討微生物、化學成分、商業外觀品質的照射探討，最後找出一個最適宜的輻射滅菌劑量及方法，提供國內相關中藥進口商、中藥廠、中醫院診所及消費者使用，以改善甘草、西洋參、白芍藥、冬蟲夏草的品質並保障國人的健康、安全。 | |
| 關鍵字：γ射線,傳統中醫,穩定度 |
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The Effects of Radiation Sterilization on the MolcularMarkers of Four Different Chinese Medicine Herbs C.J. ChengInstitute of nuclear energy research |
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| The weather of Taiwan is hot and humid. The humidity and warm temperature often cause problems of growing mildew and rod. It is hard to preserve the traditional Chinese medicines (TCM). The method of using γ-ray to destroy microorganisms is easy, rapid and effective. Therefore, the radiation ofγ-ray is broadly used by the TCM industry. However, people byγ-ray mostly noticed the effect of destroying microorganisms instead of noticing the effectiveness of the TCM be preserved. This experiment take Paeonia lactiflora, Glycyrrhiza uralensis, Panax quinquefolium and Cordyceps sinensis as samples and individually radiated by 10, 15, 20, and 30 KGy dosage of g-ray. As far as its curative marker constituents as concerned (Paeonia lactiflora: paeoniflorin; Glycyrrhiza uralensis: glycyrrhizin; Panax quinquefolium: ginsenoside Rb1, Rg1, Cordyceps sinensis: Cordycepin) be analyzed and compared with HPLC to see if its former and later target marker constituents change or not. It is to evaluate t | |
| 關鍵字：γ-ray, traditional Chinese medicines, stability |
