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CCMP87-RD-001 比較停經後婦女接受中藥治療或雌激素治療,其更年期症狀血脂肪及骨質密度之研究

  • 資料來源:中醫藥司
  • 建檔日期:87-08-30
  • 更新時間:109-04-06

比較停經後婦女接受中藥治療或雌激素治療,其更年期症狀血脂肪及骨質密度之研究

許朝欽 
國立成功大
婦女在停經後由於女性荷爾蒙的缺乏,直接產生的問題主要有三:其一為更年期症候群的出現;其二為脂肪代謝的改變,造成心臟血管疾病的增加;其三為骨質大量流失而有骨質疏鬆症之虞。 本研究即在了解正常停經年齡之40到60歲婦女其更年期症候群出現狀況,脂肪代謝以及骨質密度之情形, 同時經由助理,藉心理症狀量表 (SCL-90-R),了解臺灣地區停經後婦女之生活壓力、身心症狀及對自我影像之看法。

由於台灣人口平均年齡增長停經婦女與日俱增,其特殊的醫療與健康問題應加以重視與研究。特別是在推廣荷爾蒙補充治療之前,我們要先了解臺灣停經婦女之基本健康狀態(包括脂肪代謝和骨質密度等)以及她們所面臨之心理壓力等問題,來做為日後治療之基礎和政府推行保健政策之參考。

於停經的治療上我們擬以傳統中藥的二仙湯或加味消遙散,比較其雌激素補充療法對於更年期症狀;脂肪代謝以及骨質密度的影響。由於雌激素等荷爾蒙的補充,始終無法有足夠的統計資料能夠掃除民眾對於腫瘤產生的疑慮。因此傳統中藥的投與若能夠達到荷爾蒙補充療法類似的效果,則可以將之廣為推廣應用。

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Surveillance of climacteric symptoms lipid profile and bone density in women receiving Chininese medicine or estrogen replacement therapy


Nowadays, the health care of the menopausal women has become an important issue as the averaged female life expectancy prolonged to around 78 to 80 years old Menopause or the cessation of the menstrual cycles in women results from natural ovarian failure. There is no more follicular maturation as well as dimished ovarian sex steroids generation. Both early symptoms such as hot flush, sweating, insomnia and late sequela of osteoporosis and cardiovascular problems develop thereafter. Studies have shown that most of those menopausal symptoms can be improved using estrogen replacement therapy. However, there are some discomforts in using setrogen and the risk of increasing or even decresing the incidence of malignancy during this regime has not been clarified.

In this study, we are going to evaluate the effect of traditional Chinese medicine, Two Immortal Decoctin, Tan-Zhi Free Wander Powder, on menopausal women. Their effects on the climacteric symptoms, lipid profiles, and bone mi
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