傷寒論、金匱要略與溫病條辨治黃疸方劑對ANIT誘發實驗性黃疸性肝炎的比較研究

陳榮洲
中國醫藥學
中醫方劑治療肝炎黃疸，不論何種病毒感染，在改善臨床症狀及肝實質病變，是具有相當正面的意義。因此本研究計畫擬以奈異硫氰酸脂(ANIT, Alpha-naphthylisothiocyanate)試劑誘發黃疸性肝炎動物模型，ANIT除能誘發結合型高膽紅素血症，並能誘發膽道炎及肝損傷。

有關黃疸方面的實驗研究，在文獻上傳統方劑除了茵陳蒿湯退黃的作用機理較為學術界所重視外，其餘方劑比較少為學者所探討，故本實驗欲進一步探討傷寒論、金匱要略與溫病條辨中治黃

實驗分三組，傷寒方劑組，金匱方劑組，和溫病方劑組，三組分別進行。每組各分六小組，即控制組，損傷組，Silymarin組，和治療組三組。

本研究結果預期不僅可提供臨床中醫師在治療肝炎黃疸時有分析處方用藥的能力，在中醫內科學術上又能充實其內容。

關鍵字：肝炎黃疸、黃疸方劑、奈異硫氰酸脂試劑疸的方劑

Comparative studies of jaundice pattern prescriptions from Shan-Han-Lun, Jin-Gui-Tao-Lueh and Wen-Bing-Tian-Bian on experimental hepatitis with jaundice induced by ANIT

Jung-Chou Chen 
School of Chinese Medicine China Medical College
Chen
ANIT (Alpha-naphthylisothiocyanate)can induce hyperbilirubinemia, cholangitis and hepatotoxicity. In this study we expect to evaluate the effects of Chinese medical jaundice pattern prescriptions from Shan-Han-Lun, Jin-Gui-Tao-Lueh and Wen-Bing-Tian-Bian on experimental hepatitis with jaundice induced by ANIT in rats.The experimental method is divided into three parts：the Shan-Han group, the Jin-Gui group and Wen-Bing group. Each group is divided into six subgroup including contol subgroup, injury subgroup, silymarin subgroup and three subgroups of jaundice pattern prescriptions. The study we expect the result that will be using in Chinese clinic to treat hepatitis with jaundice on pattern identification. It will be supplying and extending the content in Chinese internal medicine.
關鍵字：Hepatitis with jaundice, jaundice pattern prescriptions and Alpha-naphthylisothiocyanate.