市售綠豆癀品質及毒性之追蹤研究

郭代璜
大仁科技大學
民間沿用的偏方中所流傳的神祕青草配方「綠豆癀」，相傳於昔日醫藥不發達年代，據說有清熱解毒功效等多種功能，可內服亦可外敷，且煉製過程相當具有獨特性，故民間常見販售綠豆癀產品。本計畫擬針對市售綠豆癀，以現代研究技術進行產品品質分析與毒性的追蹤研究。

研究內容將會以「市售綠豆癀製程實地訪查及品質分析之研究」、「市售綠豆癀產品之品質分析(如重金屬試驗、農藥殘留、微生物試驗等)」、「完成96年度計畫未鑑定之綠豆癀亞急毒性組織切片」、「市售綠豆癀產品之用途探討」、、「市售綠豆癀產品之亞慢性重覆劑量毒性試驗」、「市售綠豆癀產品對於正常細胞之毒性試驗」六大部分進行。首先比較其製程之優缺點及可能對人體產生危害之因素。接著進行市售綠豆癀產品品質分析與成分分析比較，以及探討綠豆癀的用途，再對市售綠豆癀產品進行亞慢性重覆劑量毒性試驗與正常細胞之毒性試驗，藉由瞭解綠豆癀產品或原料相關的品質檢測，進而建立產品安全性，才能替民眾的健康把關。
關鍵字：綠豆癀、品質、毒性

Investigate and track the quality and toxicity of commercial Mung bean Huang

Daih-Huang Kuo
The “mung bean huang” (progressed Mungbean) was mystical green grass formula and used as folk medicine in Taiwan and China for a long time. It was said that “mung bean huang” possessed deintoxicating effect and many kinds of physical functions. The progressed Mungbean can be taken by oral administration and also may be applied externally. The refinement process of the “mung bean huang” was very special and complicated. So the price of the product was quite high. But the quality of the product was criticized by different points. Therefore this study is aimed on the continues quality analysis of the product by the modern technology and the toxic research

The research was divides into five parts. The first work is to investigate deeply the refinement manufactured process of the market mung bean huang and collect these products. The second work is carried on the quality of analysis of the product. The tissue histology and pathology could be observed after oral repeated 90-day dose in rodents. The other work would be taken to test the cytotoxicity of the market mung bean huang product. By these quality analysis and the toxic research, it would be helpful to people health in Taiwan.
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